Major UK teams will be sending their best riders to the Monmouthshire town to compete in a event, which is round two of the prestigious HSBC/British Cycling UK Elite Circuit Series and which has also become a highlight of the sporting year for cycling in Wales.
Last year's fast and furious contest was won by Connor Swift, from the Madison-Genesis team, who raced in Wales days after becoming the new the British Cycling National Road Race champion in Northumberland.
Swift is set to return to Abergavenny this year to defend his title but could face stiff competition from his own team-mate, Newport's Commonwealth Games road race silver medalist Jon Mould, who was second behind Swift last year and, as a bit of crits specialist, has 11 Tour Series wins on his CV.
And 22-year-old Matt Gibson, who won the National Crits Series Championships last year and was third in Abergavenny in 2018, is also expected to be on the line for this year's Wales Open.
Other big names who are possibly going to ride include Olympic Games track gold medalist Ed Clancy, who is with the Vitus Pro Cycling team and is team-mates with other Abergavenny favourites Graham Briggs and Scott Thwaites plus Dylan Kerfoot-Robson, who was in the Wales team that helped Mould to his silver medal on the Gold Coast in 2018.
And rising star Zach Bridges, who lives just 15 miles from Abergavenny on the outskirts of Newport and is with the Ribble Pro team, is also expected to be an entry.
The racing on Friday July 5 starts with support events around 5.30pm and the annual Traders Race, where local businesses get a chance to ride the town centre course for fun, at around 6pm.
The Elite race, when crowds can see the stars up close, begins at 8pm. Admission to the event is free.